One of the most potent brain supplements.
As one of the most potent brain enhancing nootropic supplements, Citicoline (CDP Choline) helps to provide power and energy to brain cells to help them rejuvenate, multiply, and improve focus and concentration.
The main focal point of Citicoline is to help rejuvenate brain health by helping it structure brain cells, regenerate them, and protect the neural networks in the brain.
Research has indicated that Citicoline may benefit as a:
This means it can promote the production of phospholipids, which essentially help to repair and maintain brain cell membranes.
The brain uses a tremendous of amount of energy. In fact, about 20 percent of your body’s energy consumption is used by the brain. Citicoline helps to boost energy efficiency.
When the brain’s key chemicals associated with memory, calm thought, and attention and focus are at optimal levels, it becomes easier to get things done.
Boosting circulation to the cerebrum, it allows for better overall functionality, including clarity and focus.
Citicoline helps to protect brain cells by keeping them nourished and well maintained.
How Citicoline provides the boost your brain needs.
As with the body overall, the best way to achieve optimal levels of performance is to ensure it’s getting the proper level of nourishment. The same holds true of the brain, but that nourishment comes in the form of nutrients, oxygen, and the production of certain chemicals.
Citicoline acts as a boost for three key areas of the brain: attention span, focus, and mental energy. For older individuals who may be experiencing cognitive decline, it can even help to rejuvenate the brain, enhancing memory and possibly even reverse some degenerative effects of age related mental conditions.
Citicoline is a ‘choline donor,’ which means it’s responsible for providing the raw materials needed for the production and synthesis of two key cholines, which are:
- Phosphatidylcholine (PC): This is the building block for neurons, or brain cells. PC is used to create new brain cells and to help repair, rejuvenate, and stabilize existing brain cells, including the membranes of those cells.
- Acetylcholine (ACh): This neurotransmitter is critical for neuron to neuron signaling that’s essential for learning, memory, and recall.
It has been noted that both PC and ACh levels in the brain begin to decline with age, which has been attributed with mental decline. By boosting the consumption of Citicoline, it helps to rejuvenate these two essential brain substances.
On top of that, Citicoline’s effects can actually be amplified by the simple fact that it also helps to boost overall brain energy, which is essential for optimal mental focus and function.
Citicoline boosting brain energy.
As noted earlier, the brain consumes about 20 percent of the body’s entire store of energy. A lot of power is needed to keep the brain operating properly. By helping to boost those energy levels and stores, Citicoline also provides a key boost in cell to cell communication.
What does that mean?
Think about it like working out. When you’re low on energy and head to the gym, you won’t likely perform at optimal or ideal levels. As a result, your workout may only maintain muscle.
If your brain is operating on low energy levels, it can struggle to get through its own workout, thus leading to less retention, more difficulty with recall, and more challenges staying focused.
A more energized brain will equal sharper focus and improve brain cell replication.
Citicoline offers a synergistic benefit.
In other words, there are several benefits of this ingredient to brain health and each one builds on the other, helping to amplify the next. That can enhance the brain’s functionality.
To better understand this, consider how these benefits build on one another.
- Citicoline boosts PC and ACh production, helping to restore brain cell membrane health.
- Citicoline calls for the synthesis of neurotransmitters, which is how cells communicate with one another.
- It then improves efficiency of brain cell membranes.
- Finally, it brings everything together to help your brain ‘fire on all cylinders.’
The best part of all this is the research that backs up these benefits of Citicoline.
The Research to Back the Claims
The best way to support some tall claims would be to show the kind of research that exists to back it all up. According to Silveri et al, Citicoline in the form of Cognizin® helps to boost brain energy by 14% and neural membrane improvement by 35%.
In this particular research study, 16 men with an average age of 47 participated. Some took Cognizin® at 500 mg or 2,000 mg every day for 6 weeks. The results were those mentioned previously.
The researchers noted that Citicoline may very well help “mitigate cognitive declines associated with aging by increasing energy reserves and utilization.”
Another research study by Babb at al found that subjects taking 500 mg of Citicoline for 6 weeks showed a 7.3% increase in brain photodiesters, which helps to improve cell synthesis and ultimately verbal learning.
The subjects in this study showed improvement in verbal learning capabilities compared to those in a placebo controlled group. These researchers noted that Citicoline help to stimulate the synthesis and replacement of brain cell membrane phospholipids that could be responsible for helping to “reverse age-related changes in the brain.”
In a double blind study conducted by McGlade et al, researchers found that out of 60 women between the age of 40 and 60 who participated in the study, taking a daily dose of Cognizin® at 250 mg, 500 mg, or a placebo showed an improvement in test scoring metrics for those who had been taking to citicoline. Those subjects taking 500 mg daily showed the best results.
They concluded that citicoline “improve[d] attentional performance in middle aged women.”
While dosages for Citicoline are generally offered in either 250 mg or 500 mg capsules, research has indicated that optimal performance levels are attained when the individual consumes between 1,000 and 2,000 mg each day.
What about Side Effects?
The more significant research studies showed little to no side effects of taking Citicoline, but some smaller studies have indicated that sleep challenges, headaches, and nausea or an upset stomach can be associated with taking Citicoline.
You can find this ingredient as an antioxidant, which can be provided by supplements by itself or in the form of Cognizin®. This is branded and has a unique fermentation process that produces a water soluble, allergen free ingredient. It’s more expensive, but some consider a premium ingredient worth the extra investment.